A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction

• Dariusz Błachut,
• Joanna Szawkało and
• Zbigniew Czarnocki

Beilstein J. Org. Chem. 2016, 12, 835–845, doi:10.3762/bjoc.12.82

• display promising properties in asymmetric catalysis [19][20][21][22]. In our ongoing forensic chemistry programme directed toward the identification and synthesis of novel byproducts of illegally produced amphetamine analogues, we described the synthesis of several new nitrogen heterocycles. Among them

Synthesis and stability study of a new major metabolite of γ-hydroxybutyric acid

• Ida Nymann Petersen,
• Jesper Langgaard Kristensen,
• Christian Tortzen,
• Torben Breindahl and
• Daniel Sejer Pedersen

Beilstein J. Org. Chem. 2013, 9, 641–646, doi:10.3762/bjoc.9.72

• analytical methods. Using NMR we show that GHB glucuronide 2 is highly stable towards aqueous hydrolysis within the pH range normally observed for urine even at elevated temperature. Keywords: analytical chemistry; cabohydrate chemistry; forensic chemistry; glucuronide; γ-hydroxybutyric acid; metabolite

• demonstrated to be highly stabile towards aqueous hydrolysis within the pH range normally observed for urine even at elevated temperature for several days, making it suitable for method development within analytical and forensic chemistry. Experimental General For reactions conducted under anhydrous conditions